Computational Brain Science
The scientific mission of the Computational Brain Science Lab at EECS is to be at the forefront of mathematical modeling, quantitative analysis and mechanistic understanding of brain function. We perform research on (i) computational modeling of biological brain function and on (ii) developing theory, algorithms and software for building computer systems that can perform brain-like functions. Our research answers scientific questions and develops methods in these fields. We integrate results from our science-driven brain research into our work on brain-like algorithms and likewise use theoretical results about artificial brain-like functions as hypotheses for biological brain research.
Mathematical modeling of brain function and dysfunction
Our research on biological brain function includes sensory perception (vision, hearing, olfaction), cognition (action selection, memory, learning) at different levels of biological detail (molecular, cellular, network) and mathematical/functional description.
We develop methods, computational models, perform multi-scale neural simulations, build software and AI approaches for investigating biological brain dynamics and function / dysfunction, and devise machine learning/AI techniques for multi-modal brain data analysis.
Brain-like computing
Our research on brain-like computing concerns the development of methods and algorithms for perceptual systems that extract information from sensory signals (images, video and audio), for analysis of functional brain images and EEG/MEG data, learning for autonomous agents as well as the development of computational architectures (both software and hardware) for neural information processing. Our brain-inspired approach to computing also applies more generically to other computer science problems such as pattern recognition, associative memory, data analysis, decision support and intelligent systems towards brain-like AI architectures for edge as well as cloud computing.
Long term vision
Our long-term vision is to contribute to (i) a deeper understanding of the computational mechanisms underlying biological brain function, and (ii) better theories, methods and algorithms for perceptual and intelligent systems that produce brain-like functions by (iii) performing interdisciplinary and cross-fertilizing research on both biological and artificial brain-like functions.
On the one hand, biological brains provide existence proofs for guiding our research on artificial perceptual and intelligent systems. On the other hand, applying Richard Feynman’s famous statement ”What I cannot create I do not understand” to brain science implies that we can only claim to fully understand the computational mechanisms underlying biological brain function if we can build and implement corresponding computational mechanisms on a computerized system that performs similar brain-like functions.
Researchers
The research at the Computational Brain Science Lab is mainly performed within the following areas under the supervision of eight principal investigators (listed alphabetically).
Jörg Conradt: neurorobotics, neuromorphic systems, engineering applications of neural computation, low-power and low-latency sensory processing, event-based vision algorithms and systems, brain-inspired closed-loop control for autonomous mobile robotics
Erik Fransén: time-series machine learning, eye-tracking data, EEG/MEG data, synapse protein data, computational neuroscience, computational pharmacology, pain, epilepsy, working memory, intrinsic excitability, dendritic integration, ion channel kinetics, ion channel modulation, entorhinal cortex, hippocampus, C-fiber, peripheral nerve
Jeanette Hellgren-Kotaleski: computational neuroscience, computational systems biology, kinetic modeling, basal ganglia in health and disease, reward dependent learning, neuroinformatics, multi-scale approaches, FAIR modeling pipelines
Pawel Herman: computational neuroscience, cortical modelling, associative memory, cortical dynamics and oscillations, working and episodic memory, brain data analysis, connectionist systems, brain-like computing, neuro-AI, brain-computer interfac
Arvind Kumar: controllability of neuronal networks, network of networks, spiking neuron network dynamics, correlations, synchrony and oscillations, information flow in neuronal networks, cortico-basal ganglia interactions, neuromodulation, epilepsy, Parkinson's disease, dynamics of brain diseases
Anders Lansner: computational neuroscience, neuromorphic systems and brain-like machine learning, semi-detailed and abstract non-spiking/spiking neural network models of cortex, cortical associative memory including working memory, decision making and temporal sequence learning.
Tony Lindeberg: vision, computer vision, scale-space theory, visual and auditory receptive fields, feature detection, image descriptors, object recognition, video analysis, covariant and invariant deep networks, computational modelling of visual and auditory perception, normative theory for neural mechanisms
Projects
Current
Covariant and invariant deep networks
Funded by the Swedish Research Council 2023-2026
Previous projects
HBP, The Human Brain Project,
Neurorobotics sub-project SP10
Funded by European Commission as a FET flagship, 2016-2020
Integrating new experimental findings into a novel Hebbian plasticity theory of working memory and neural binding
Funded by The Swedish Research Council 2019-2022
Scale-space theory for covariant and invariant visual perception
Funded by The Swedish Research Council 2019-2022
How does neuronal diversity affect the dynamics and function of networks in the brain
Funded by The Swedish Research Council 2019-2022
Scale-space theory for invariant and covariant visual receptive fields
Funded by The Swedish Research Council, 2015-2018
Time-causal receptive fields for computer vision and computational modelling of biological vision
Funded by Stiftelsen Olle Engkvist Byggmästare, 2016-2017
Brain-inspired computing approach to exploratory analysis of multivariate spatiotemporal brain signals for non-invasive diagnostic evaluation.
Funded by Vinnova via Stockholm Brain Institute, 2014-2016
Brain-like algorithms for temporal sequence processing - recognition, generation, and learning
Funded by Swedish Science Council, 2012-2016
StratNeuro – Strategic Research Area Neuroscience, assistant professor position in computational neuroscience.
Governmental funding via Swedish Science Council, 2010-2016
HBP, The Human Brain Project,
Neuromorphic computing sub-project SP9
Funded by European Commission as a FET flagship, 2013-2016
BrainScaleS – Brain-inspired multiscale computation in neuromorphic hybrid systems
Funded by European Commision FET-Proactive FP7, 2011-2015
Funded by European Commision, Erasmus Mundus, 2010-2015
Idealized computational models of auditory receptive fields
CSC Small Visionary Project, 2013-2014
Image descriptors and scale-space theory for spatial and spatio-temporal recognition
Funded by The Swedish Research Council, 2011-2014