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Towards a framework for patient specific simulation of disease and clinical interventions in the human heart

Time: Thu 2019-05-23 11.00 - 12.00

Location: Room 4423, Lindstedtsvägen 5, KTH, Stockholm

Participating: Frida Svelander, CST/EECS/KTH


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Patient-specific models in medicine offer an emerging technology for simulation of disease progression and clinical interventions. Such simulations have the potential to offer clinical decision support, and to strengthen evidence-based medical decisions. In this seminar, we present our work on a framework for patient-specific simulation of left ventricular (LV) hemodynamics [1, 2]. In particular, we focus on the extension of the pre-existing LV model with a simple planar, data-driven parameterized model of the mitral valve (MV).


  1. Larsson, D. et al, IEEE Trans Med Imaging, 36(11):2261-2275, 2017.

  2. Hoffman, J. et al, Jülich Aachen Research Alliance (JARA) High-Performance Computing Symposium, Springer, 58-69, 2016.