The future of body fluid biomarkers research and implementation: validate and conquer
Significant technological advances have enabled a deeper understanding of the proteome in biological fluids and the emergence of countless ‘new biomarker candidates’. The lecture discusses some of the most important factors behind the high failure rate in the transfer of new biomarkers to clinical routine.
Time: Wed 2025-08-20 14.00 - 15.00
Location: SciLifeLab, Alfa-2-Milky Way-A2631
Language: English
Participating: Claudia Fredolini
Biological fluids have been widely used in both ancient and contemporary diagnostic practices. The undeniable advantage offered by minimally invasive tools for disease diagnosis and monitoring has driven technical and clinical research focused on the identification of new protein biomarkers measurable in biological fluids.
In the past few decades, significant technological advancements enabled a deeper knowledge of the proteome of biological fluids and the emergence of countless “new biomarker candidates”. Nevertheless, the research of biomarkers in body fluids is far from successful as the translation of new biomarkers into clinical routine has been very limited.
This lecture will cover some of the key factors from which the high rate of failure in translation stemmed from. Future perspective, emerging technologies and potential game changing for the field will be discussed.